THE FIRST STEREOSELECTIVE BIFUNCTIONALIZATION OF 4-QUINOLONES WITH ORGANOMETALLICS AND N-HALOSUCCINIMIDES TO 2,3-TRANS DISUBSTITUTED TETRAHYDROQUINOLONES - EXPECTED AND UNEXPECTED RESULTS

Authors
BEIFUSS U FEDER G BES T USON I
Citation
U. Beifuss et al., THE FIRST STEREOSELECTIVE BIFUNCTIONALIZATION OF 4-QUINOLONES WITH ORGANOMETALLICS AND N-HALOSUCCINIMIDES TO 2,3-TRANS DISUBSTITUTED TETRAHYDROQUINOLONES - EXPECTED AND UNEXPECTED RESULTS, Synlett, (6), 1998, pp. 649
Citations number
22
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
6
Year of publication
1998
Database
ISI
SICI code
0936-5214(1998):6<649:TFSBO4>2.0.ZU;2-O
Abstract
The C-2-addition of organometallic reagents to 4-quinolones followed b y reaction with N-halosuccinimides provides a short and diastereoselec tive entry for the preparation of 2,3-trans disubstituted tetrahydroqu inolones.