A patient suffering from infantile-onset insulin-dependent diabetes me
llitus is reported in whom immune pancytopenia (Evans' syndrome) devel
oped at the age of 2 1/2 years. Hepatosplenomegaly, chronic lymphadeno
pathy, and elevated levels of immunoglobulins G and M were also presen
t. The course of Evans' syndrome was fatal in this patient. The associ
ation of Evans' syndrome with other immune disorders is discussed.