STUDIES ON ORGANOPHOSPHORUS COMPOUNDS .78. NEW ASPECTS ON THE INDUCEDASYMMETRIC ADDITION OF DIALKYL PHOSPHITE TO ALDIMINES - AN EFFECTIVE SYNTHESIS OF CHIRAL 1-ARYLPHOSPHONOGLYCINE DERIVATIVES
Cy. Yuan et al., STUDIES ON ORGANOPHOSPHORUS COMPOUNDS .78. NEW ASPECTS ON THE INDUCEDASYMMETRIC ADDITION OF DIALKYL PHOSPHITE TO ALDIMINES - AN EFFECTIVE SYNTHESIS OF CHIRAL 1-ARYLPHOSPHONOGLYCINE DERIVATIVES, Phosphorus, sulfur and silicon and the related elements, 81(1-4), 1993, pp. 27-35
Addition of dialkyl phosphites to Schiff bases derived from (R)-2-meth
oxy-1-phenylethylamine or (R)-phenylglycine methyl ester afforded (1R,
1'R)-1-arylphosphonoglycine derivatives with moderate to high diaster
eoselectivity. The influence of catalysts and solvents and the structu
ral effects of the substrates on this stereochemical process were repo
rted.