INTRINSIC-VISCOSITY CALCULATED OUT OF SINGLE-POINT MEASUREMENTS FOR CHONDROITIN-4-SULFATE AND CHONDROITIN-6-SULFATE SOLUTIONS

The differences in the structure of polymer chain between the chondroi tin-4-sulfate (C4-S) and the chondroitin-6-sulfate (C6-S) are reflecte d in the intrinsic viscosity values calculated starting from the tradi tional methods of Huggins, Kraemer, Mead and Fouss, and Martin, and by the method for a single-point determination of intrinsic viscosity [e ta]. For the range between 0.4 and 0.5% (w/v) concentrations, we get a n agreement in the intrinsic viscosity values. The chains of both poly mers present a flexible structure and are not ramified between 0.28 an d 1.00% (w/v) concentrations. (C) 1998 Elsevier Science B.V. All right s reserved.