The recognition of heartburn and acid regurgitation as manifestations
of gastro-oesophageal reflux disease (GORD), and the suppression of th
ese symptoms with therapy, represent an over-simplistic approach to th
e reflux patient. For GORD, as for other gastrointestinal disorders, i
t is evident that many patients suffer a greater impairment of well-be
ing than has been appreciated hitherto, and that this impairment can b
e quantified using modern quality of life measuring techniques, Succes
sful treatment normalizes quality of life in a manner which is substan
tially, but not wholly, predictable from symptom responses or the heal
ing of oesophagitis, These observations raise the possibility that phy
sicians' therapeutic intentions do not always match the patients' wish
es. The appraisal of health status, or quality of life (QOL), is incre
asingly important in defining the implications of disease and for asse
ssing the outcome of therapy. Hitherto, QOL evaluations have seemed re
levant to circumstances of major physical disability and for patients
receiving potentially unpleasant treatments, such as cancer chemothera
py, but it is now evident that QOL evaluation has much wider applicabi
lity, including relevance to common gastrointestinal disorders such as
GORD, Eur J Gastroenterol Hepatol 10:451-454 (C) 1998 Lippincott-Rave
n Publishers.