BASE-SPECIFIC INTERACTION OF POLYMERS CONTAINING ADENINE - EFFECT OF CHIRAL SPACER ON THE INTERACTION WITH POLYNUCLEOTIDE

Authors
INAKI Y KAMO S MIYATA M
Citation
Y. Inaki et al., BASE-SPECIFIC INTERACTION OF POLYMERS CONTAINING ADENINE - EFFECT OF CHIRAL SPACER ON THE INTERACTION WITH POLYNUCLEOTIDE, Reactive & functional polymers, 37(1-3), 1998, pp. 189-198
Citations number
6
Categorie Soggetti
Polymer Sciences","Engineering, Chemical","Chemistry Applied
Journal title
Reactive & functional polymers → ACNP
ISSN journal
13815148
Volume
37
Issue
1-3
Year of publication
1998
Pages
189 - 198
Database
ISI
SICI code
1381-5148(1998)37:1-3<189:BIOPCA>2.0.ZU;2-N
Abstract
Polyethyleneimine derivatives of adenine with L- and D-serine as space rs were prepared. The polymer having D-serine spacer 2 gave a stable p olymer complex with poly(uridylic acid) (poly U), but the polymer havi ng L-serine spacer 1 gave an unstable polymer complex. The reason was concluded to be caused by the steric repulsion of L-serine units along the polymer chain when the polymer formed polymer complex with poly U . (C) 1998 Elsevier Science B.V. All rights reserved.