REACTIONS OF MELATONIN WITH RADICALS IN DEOXYGENATED AQUEOUS-SOLUTION

Authors
STASICA P ULANSKI P ROSIAK JM
Citation
P. Stasica et al., REACTIONS OF MELATONIN WITH RADICALS IN DEOXYGENATED AQUEOUS-SOLUTION, Journal of radioanalytical and nuclear chemistry, 232(1-2), 1998, pp. 107-113
Citations number
39
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Analytical","Nuclear Sciences & Tecnology
Journal title
Journal of radioanalytical and nuclear chemistry → ACNP
ISSN journal
02365731
Volume
232
Issue
1-2
Year of publication
1998
Pages
107 - 113
Database
ISI
SICI code
0236-5731(1998)232:1-2<107:ROMWRI>2.0.ZU;2-M
Abstract
Reactions of melatonin (N-acetyl-5-methoxytryptamine) with radiolytica lly generated radicals were studied. Reaction of melatonin with OH rad icals is diffusion-controlled (k=1.2.10(10) dm(3) mol(-1).s(-1)), the main (but not the only one) intermediate being the indolyl-type radica l, while the rate constant for the reaction with hydrated electrons is k=4.3.10(8) dm(3).mol(-1).s(-1). Melatonin is capable of scavenging t ert-butanol radicals, while its reactivity towards polymer radicals of poly(acrylic acid) and poly(vinyl pyrrolidone) is very low.