P. Satz et al., DEPRESSION, COGNITION, AND FUNCTIONAL CORRELATES OF RECOVERY OUTCOME AFTER TRAUMATIC BRAIN INJURY, Brain injury, 12(7), 1998, pp. 537-553
The present study investigated the prevalence and magnitude of depress
ive symptomatology in a sample of patients who had sustained traumatic
brain injury (TBI) six months earlier. Depression was examined as a f
unction of recovery outcome status, and its association with neuropsyc
hological functioning, personal competency, and employability was also
explored. Subjects were 100 patients who had previously sustained mod
erate-to-severe TBI who were enrolled as research subjects in the UCLA
Brain Injury Research Center, and 30 matched control subjects who had
sustained traumatic injuries other than to the head six months prior
to evaluation. The results showed a significant association between de
pression and recovery status as measured by the Glasgow Outcome Scale
(GOS). A significant majority of depressed subjects were found in the
poorer dos outcome groups (severe and moderate disability), compared t
o TBI subjects who had good GOS outcomes, and control subjects. This a
ssociation was also reflected in the magnitude of the mean depression
scores on two self-report measures of depression. However, no associat
ion was found between depression status and performance on the neurops
ychological measures. Effects of depression were found only on an exam
iner-rated Patient Competency scale, and a metacognition measure based
on self-report. These results are discussed in terms of brain injury
severity, recovery status, and metacognition issues in TBI and other d
isorders.