We study the issue of the cosmological constant in quantum cosmology c
ombined with the Brans-Dicke gravitational theory. Using the minisuper
space approximation, we build up the Wheeler-De Witt equation and then
obtain the wave function of the universe by further assuming the WKB
approximation under the boundary condition proposed by Vilenkin. It is
shown that the amplitude of the resulting wave function, which repres
ents an expanding universe, reaches its peaks if the cosmological cons
tant vanishes.