Emerging telemedicine applications require the ability to exploit dive
rse and geographically distributed resources. Highspeed networks are u
sed to integrate advanced visualization devices, sophisticated instrum
ents, large databases, archival storage devices, PCs, workstations, an
d supercomputers. This form of telemedical environment is similar to n
etworked virtual supercomputers, also known as metacomputers. Metacomp
uters are already being used in many scientific application areas. In
this article, we analyze requirements necessary for a telemedical comp
uting infrastructure and compare them with requirements found in a typ
ical metacomputing environment. We will show that metacomputing enviro
nments can be used to enable a more powerful and unified computational
infrastructure for telemedicine. The Globus metacomputing toolkit can
provide the necessary low level mechanisms to enable a large scale te
lemedical infrastructure. The Globus toolkit components are designed i
n a modular fashion and can be extended to support the specific requir
ements for telemedicine. (C) 1998 Elsevier Science B.V.