Two new pyrrole alkaloids, solsodomine A and B, were isolated from the
fresh berries of Solanum sodomaeum L., collected from the Libyan dese
rt. The structures of these compounds were established by 2D-NMR, incl
uding N-15 NMR spectroscopy and chemical degradation. Solsodomine A(1)
shows activity against Mycobacterium intracellulare. This is the firs
t report of pyrrole alkaloids from the genus Solanum.