DIHYDROTUBASTRINES - PHENETHYLGUANIDINE ANALOGS FROM THE INDO-PACIFICMARINE SPONGE PETROSIA CF. CONTIGNATA

Authors
SPERRY S CREWS P
Citation
S. Sperry et P. Crews, DIHYDROTUBASTRINES - PHENETHYLGUANIDINE ANALOGS FROM THE INDO-PACIFICMARINE SPONGE PETROSIA CF. CONTIGNATA, Journal of natural products, 61(6), 1998, pp. 859-861
Citations number
22
Categorie Soggetti
Chemistry Medicinal","Plant Sciences","Pharmacology & Pharmacy",Chemistry
Journal title
Journal of natural products → ACNP
ISSN journal
01633864
Volume
61
Issue
6
Year of publication
1998
Pages
859 - 861
Database
ISI
SICI code
0163-3864(1998)61:6<859:D-PAFT>2.0.ZU;2-J
Abstract
Two phenethylguanidine derivatives, 7,8-dihydrotubastrine (1) and 4-de oxy-7,8-dihydrotubastrine (2), along with the sterol xestobergsterol A (3), were isolated from the marine sponge Petrosia cf. contignata. Th e structures of the new natural products 1 and 2 were based on spectro scopic data and comparison to the literature properties for semisynthe tic 1. This is the first example from this compound class with a satur ated acyclic C2 unit.