There has been a recent resurgence of interest in implementing brachyt
herapy in the management of nasopharyngeal carcinoma, not only as trea
tment for recurrent disease, where it has secured a notable role, but
also as an elective boost following external beam irradiation in an at
tempt to improve local control. Examination of the use of nasopharynge
al brachytherapy over nearly the last century may provide guidance for
such endeavors and encourage further evolution of these techniques. T
hroughout this interval, ingenuity has prevailed in attempts to treat
a secluded anatomical site which has been difficult to access, explore
, and implant in an acceptable manner.