This article explores the factors that influence the decision to initi
ate a drug research project. The contribution which strategic marketin
g might make to the process is examined as well as the possible reason
s why such contributions often are suboptimal. Possible obstacles to c
onnecting research and strategic marketing functions effectively inclu
de: Historically, a poor record of sales forecasting; Differing priori
ties and time frames, language, and value systems; Poor organization a
nd configuration, career trajectories, and stability. Proposals are ma
de to improve the dynamics at this important interface. Drug Dev. Res.
43:143-148, 1998. (C) 1998 Wiley-Liss, Inc.