Oxygen concentrations have been measured using the so called 'Clark ce
ll' for a long time. In this paper, first some drawbacks of the Clark
cell are discussed, with special attention towards miniaturization of
the sensor. Subsequently, the use of potentiometric sensors is discuss
ed. In both the miniaturized Clark cell and in the potentiometric sens
or a reference electrode is needed, which is hard to fabricate using t
hin him techniques. For this reason a novel way of carrying out potent
iometric measurements, using a specially developed type of potentiomet
ric oxygen sensor, is described. As the measurand the threshold voltag
e of a FET-structure having an iridium oxide gate is used, rather than
the electrode potential. The potential advantages of such a sensor co
mpared with the Clark cell are examined and the theoretical response o
f the sensor is derived. In addition some relevant experiments are des
cribed. (C) 1998 Elsevier Science S.A. All rights reserved.