MICROARRAYS - BIOTECHNOLOGYS DISCOVERY PLATFORM FOR FUNCTIONAL GENOMICS

Citation
M. Schena et al., MICROARRAYS - BIOTECHNOLOGYS DISCOVERY PLATFORM FOR FUNCTIONAL GENOMICS, Trends in biotechnology, 16(7), 1998, pp. 301-306
Citations number
33
Categorie Soggetti
Biothechnology & Applied Migrobiology
Journal title
ISSN journal
01677799
Volume
16
Issue
7
Year of publication
1998
Pages
301 - 306
Database
ISI
SICI code
0167-7799(1998)16:7<301:M-BDPF>2.0.ZU;2-A
Abstract
Advances in microarray technology enable massive parallel mining of bi ological data, with biological chips providing hybridization-based exp ression monitoring, polymorphism detection and genotyping on a genomic scale. Microarrays containing sequences representative of all human g enes may soon permit the expression analysis of the entire human genom e in a single reaction. These 'genome chips' will provide unprecedente d access to key areas of human health, including disease prognosis and diagnosis, drug discovery, toxicology, aging, and mental illness. Mic roarray technology is rapidly becoming a central platform for function al genomics.