NOT JUST PRETTY EYES - DROSOPHILA EYE-COLOR MUTATIONS AND LYSOSOMAL DELIVERY

Authors
LLOYD V RAMASWAMI M KRAMER H
Citation
V. Lloyd et al., NOT JUST PRETTY EYES - DROSOPHILA EYE-COLOR MUTATIONS AND LYSOSOMAL DELIVERY, Trends in cell biology, 8(7), 1998, pp. 257-259
Citations number
25
Categorie Soggetti
Cell Biology
Journal title
Trends in cell biology → ACNP
ISSN journal
09628924
Volume
8
Issue
7
Year of publication
1998
Pages
257 - 259
Database
ISI
SICI code
0962-8924(1998)8:7<257:NJPE-D>2.0.ZU;2-E
Abstract
Analysis of Drosophila eye-colour mutations has made seminal contribut ions to the fields of genetics and biochemistry. Recent findings sugge st that a subset of eye-colour genes is crucial for vesicular transpor t of proteins to pigment grannies, specialized lysosomes of eye-pigmen t cells. Thus, classical work describing more than 85 eye-colour mutat ions and their genetic interactions offers a remarkable, untapped reso urce for the genetic analysis of protein delivery to lysosomes.