DUAL-ISOTOPE SPECT IN MALIGNANT JACODS-SYNDROME

A case is presented of metastatic tumor causing Jacod's syndrome: tota l ophthalmoplegia, blindness, and trigeminal neuralgia. Abnormal soft tissue invading the orbital apex, anterior clinoid process, and cavern ous sinus was difficult to assess by CT and MRI, but dual-isotope SPEC T including Tc-99m HMDP bone imaging and Tl-201 tumor imaging strongly suggested that the cause of this rare syndrome was a small metastatic tumor. Although the therapeutic effect was also difficult to assess b y anatomic imaging alone, dual-isotope SPECT after radiation therapy s howed a decline of tumor viability.