SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF 2,4-DIHYDRO-4-BENZYL-5-(ISOMERIC PYRIDYL)-3H-1,2,4-TRIAZOLE-3-THIONES

Authors
IQBAL R RAMA NH AHMAD N ZAMANI K EBRAHIM S IQBAL N
Citation
R. Iqbal et al., SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF 2,4-DIHYDRO-4-BENZYL-5-(ISOMERIC PYRIDYL)-3H-1,2,4-TRIAZOLE-3-THIONES, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 37(5), 1998, pp. 506-509
Citations number
12
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry → ACNP
ISSN journal
03764699
Volume
37
Issue
5
Year of publication
1998
Pages
506 - 509
Database
ISI
SICI code
0376-4699(1998)37:5<506:SAAAO2>2.0.ZU;2-F
Abstract
Intramolecular cyclization of the: three isomeric 1,4-disubstituted th iosemicarbazides 3a-c in aqueous sodium hydroxide affords 2,4-dihydro- 4-(benzyl)-5-(isomeric pyridyl)-3H-1,2,4-triazole-3-thiones 4a-c. The antibacterial activity of these compounds has been determined against seventeen, gram positive and gram negative microorganisms.