CHANGES IN DENDRITIC STRUCTURE AND FUNCTION FOLLOWING HIPPOCAMPAL-LESIONS - CORRELATIONS WITH DEVELOPMENTAL EVENTS

Recovery after nervous system lesions may lead to partial re-instituti on of developmental schemes and processes. Here we review several of t hese proposed schemes, with the conclusion that though some processes may involve re-expression of embryonic phenotypes, there are many proc esses invoked during recovery from lesions that do not mirror developm ental phenomena. The inability to fully revert to embryonic schemes be cause of adult phenotype may partially account for the decreased recov ery observed in adults compared to that noted after lesions during dev elopment. (C) 1998 Published by Elsevier Science Ltd. All rights reser ved.