NEOCLERODANE DITERPENOIDS FROM SCUTELLARIA-LATERIFLORA

Three new diterpenoids, scutelaterins A-C, have been isolated from Scu tellaria lateriflora and their structures established as (11S,13S,16S) -2 beta,6 alpha,19-triacetoxy-4 alpha,18;11,16;15,16-triepoxy-neo-cler od-14-ene (scutelaterin A), (11S,13S,16S)-6 alpha,19-diacetoxy-2 beta- (2'-methyl)butyryloxy-4 alpha,18;11,16;15,16-triepoxy-neo-clerod-14-en e (scutelaterin B) and (11S,13S,15R and S)-6 alpha,19-diacetoxy-2 beta -(2'-methyl)butyryloxy-4 alpha,18;11,16;15,16- triepoxy-neo-clerodan-1 5-ol (scutelaterin C) by chemical and spectroscopic means. In addition , the already known neo-clerodanes ajugapitin and scutecyprol A were a lso found in the same source. (C) 1998 Elsevier Science Ltd. All right s reserved.