BETA-AMINO TERTIARY CYCLOALKANOLS FOR THE ENANTIOSELECTIVE PROTONATION OF ENOLIC SPECIES PRODUCED BY A PALLADIUM-INDUCED CASCADE REACTION

Authors
ABOULHODA SJ REINERS I WILKEN J HENIN F MARTENS J MUZART J
Citation
Sj. Aboulhoda et al., BETA-AMINO TERTIARY CYCLOALKANOLS FOR THE ENANTIOSELECTIVE PROTONATION OF ENOLIC SPECIES PRODUCED BY A PALLADIUM-INDUCED CASCADE REACTION, Tetrahedron : asymmetry, 9(11), 1998, pp. 1847-1850
Citations number
22
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
9
Issue
11
Year of publication
1998
Pages
1847 - 1850
Database
ISI
SICI code
0957-4166(1998)9:11<1847:BTCFTE>2.0.ZU;2-K
Abstract
The palladium-induced cleavage of beta-ketoesters and enol carbonates derived from alpha-alkylated 1-indanones and 1-tetralones in the prese nce of substoichiometric amounts of various (S)-aminocycloalkanols led to optically active (R)-alpha-alkylated indanones and tetralones with enantiomeric excesses of up to 72%. (C) 1998 Elsevier Science Ltd, Al l rights reserved.