DETERMINATION OF NICKEL IN BIOLOGICAL SAMPLES BY INDUCTIVELY-COUPLED PLASMA-ATOMIC EMISSION-SPECTROMETRY AFTER EXTRACTION WITH S[PHENYL-(2-PYRIDYL)METHYLENE]THIOCARBONOHYDRAZIDE
Ev. Alonso et al., DETERMINATION OF NICKEL IN BIOLOGICAL SAMPLES BY INDUCTIVELY-COUPLED PLASMA-ATOMIC EMISSION-SPECTROMETRY AFTER EXTRACTION WITH S[PHENYL-(2-PYRIDYL)METHYLENE]THIOCARBONOHYDRAZIDE, Journal of analytical atomic spectrometry, 8(6), 1993, pp. 843-846
A sensitive inductively coupled plasma atomic emission spectrometric m
ethod for the determination of trace amounts of nickel after extractio
n of the metal into isobutyl methyl ketone (IBMK) containing is[phenyl
(2-pyridyl)methylene]thiocarbonohydrazide (BPTH) is described. A syste
matic study was made to determine the optimum conditions for extractio
n of the metal into IBMK. The chief advantage of the method lies in th
e maximum allowable aqueous-to-organic phase volume ratio of 37. The d
etection and quantification limits for nickel were 0.3 and 1.1 ng ml-1
, respectively, and the calibration is linear from 0.4 to at least 150
ng ml-1. The method has been used for the determination of nickel in
various biological samples [mineralized by microwave digestion in seal
ed poly(tetrafluoroethylene) containers], as well as in human urine, w
ith good results.