POLINA - DETECTION AND EVALUATION OF SINGLE AMINO-ACID SUBSTITUTIONS IN PROTEIN SUPERFAMILIES

Authors
LEVIN S SATIR BH
Citation
S. Levin et Bh. Satir, POLINA - DETECTION AND EVALUATION OF SINGLE AMINO-ACID SUBSTITUTIONS IN PROTEIN SUPERFAMILIES, BIOINFORMATICS, 14(4), 1998, pp. 374-375
Citations number
8
Categorie Soggetti
Computer Science Interdisciplinary Applications","Biology Miscellaneous","Computer Science Interdisciplinary Applications","Biochemical Research Methods
Journal title
BIOINFORMATICS → ACNP
ISSN journal
13674803
Volume
14
Issue
4
Year of publication
1998
Pages
374 - 375
Database
ISI
SICI code
1367-4803(1998)14:4<374:P-DAEO>2.0.ZU;2-D
Abstract
Motivation and results: An algorithm is described for the quick identi fication and evaluation of amino acid substitutions in multiple protei n sequence alignment. The strategy is based on the calculation of a re lative conservation index for an amino acid at each position of the al ignment. The algorithm is implemented in the computer-program POLINA ( Protein Oriented LINear Analysis) which provides a summary of analysis in a format suitable for import into a graphing program.