SYNTHESIS OF ENANTIOPURE SUBSTITUTED AZIRIDINES BY DIASTEREOSELECTIVEN-BROMOCYCLIZATION AND NUCLEOPHILE-MEDIATED REGIOSELECTIVE OPENING

Authors
AGAMI C AMIOT F COUTY F DECHOUX L
Citation
C. Agami et al., SYNTHESIS OF ENANTIOPURE SUBSTITUTED AZIRIDINES BY DIASTEREOSELECTIVEN-BROMOCYCLIZATION AND NUCLEOPHILE-MEDIATED REGIOSELECTIVE OPENING, Tetrahedron letters, 39(30), 1998, pp. 5373-5374
Citations number
6
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
30
Year of publication
1998
Pages
5373 - 5374
Database
ISI
SICI code
0040-4039(1998)39:30<5373:SOESAB>2.0.ZU;2-Y
Abstract
Enantiopure beta-substituted aziridines were prepared from (S)-phenylg lycinol through a key N-bromocyclization of an unsaturated iminoether. A total control of the regioselectivity was observed during the openi ng of these aziridines by various nucleophiles (N-3(-), H2O, EtOH, Me2 CuLi). (C) 1998 Elsevier Science Ltd. All rights reserved.