CHEMOTACTIC RESPONSES OF TUNICATE (UROCHORDATA, ASCIDIACEA) HEMOCYTESIN-VITRO

Citation
Da. Raftos et al., CHEMOTACTIC RESPONSES OF TUNICATE (UROCHORDATA, ASCIDIACEA) HEMOCYTESIN-VITRO, Journal of invertebrate pathology (Print), 72(1), 1998, pp. 44-49
Citations number
45
Categorie Soggetti
Zoology
ISSN journal
00222011
Volume
72
Issue
1
Year of publication
1998
Pages
44 - 49
Database
ISI
SICI code
0022-2011(1998)72:1<44:CROT(A>2.0.ZU;2-X
Abstract
A number of molecules were found to alter the motility of tunicate hem ocytes. Bacterial lipopolysaccharide (LPS) significantly enhanced cell mobility relative to non-stimulated controls. Responses to LPS mere n ot directional and so represented chemokinesis. In contrast, checkerbo ard analyses indicated that two tunicate hemolymph proteins, tunIL1-al pha and -beta, stimulated truly directional chemotaxis by hemocytes. T he data suggest that tunIL1 proteins may contribute to defense by alte ring the localization of immunocompetent cells. (C) 1998 Academic Pres s.