Da. Raftos et al., CHEMOTACTIC RESPONSES OF TUNICATE (UROCHORDATA, ASCIDIACEA) HEMOCYTESIN-VITRO, Journal of invertebrate pathology (Print), 72(1), 1998, pp. 44-49
A number of molecules were found to alter the motility of tunicate hem
ocytes. Bacterial lipopolysaccharide (LPS) significantly enhanced cell
mobility relative to non-stimulated controls. Responses to LPS mere n
ot directional and so represented chemokinesis. In contrast, checkerbo
ard analyses indicated that two tunicate hemolymph proteins, tunIL1-al
pha and -beta, stimulated truly directional chemotaxis by hemocytes. T
he data suggest that tunIL1 proteins may contribute to defense by alte
ring the localization of immunocompetent cells. (C) 1998 Academic Pres
s.