THE COLLABORATIVE HOSPITAL TRANSFUSION STUDY - VARIATIONS IN USE OF AUTOLOGOUS BLOOD ACCOUNT FOR HOSPITAL DIFFERENCES IN RED-CELL USE DURING PRIMARY HIP AND KNEE SURGERY
Wh. Churchill et al., THE COLLABORATIVE HOSPITAL TRANSFUSION STUDY - VARIATIONS IN USE OF AUTOLOGOUS BLOOD ACCOUNT FOR HOSPITAL DIFFERENCES IN RED-CELL USE DURING PRIMARY HIP AND KNEE SURGERY, Transfusion, 38(6), 1998, pp. 530-539
BACKGROUND: Red cell use in patients undergoing Diagnosis Related Grou
p (DRG) 209 procedures (major joint and limb reconstruction procedures
of the lower extremities) has been shown to have large, unexplained i
nterhospital variations.STUDY DESIGN AND METHODS: Abstracted records o
f 2590 consecutive DRG 209 patients at five university hospitals from
January 1992 to December 1993 were stratified by procedure and preoper
ative blood deposit status. Patient characteristics and transfusion an
d in-hospital outcomes were compared across hospitals. RESULTS: Blood
use among patients who did not preoperatively deposit blood was simila
r across hospitals. Significant differences were found across hospital
s for total hip replacement patients in the percentage of patients pre
operatively depositing blood (59-80%), percentage of patients receivin
g transfusion(s) (51 to >99%), the mean number of units collected per
patient (1.6-2.9), and the mean number of unused autologous units per
100 patients (1-185). No significant differences were found in the per
centage of those who deposited blood and then required allogeneic unit
s. There was little variability in length of hospital stay or in last
hematocrits. Findings were similar for total knee replacement patients
. CONCLUSIONS: Interhospital variations in red cell use for primary to
tal hip and knee reconstruction are primarily due to hospital-specific
differences in autologous blood collection and transfusion.