EVIDENCE THAT PORCINE NATIVE 5-HT3 RECEPTORS DO NOT CONTAIN NICOTINICACETYLCHOLINE-RECEPTOR SUBUNITS

Authors
FLETCHER S LINDSTROM JM MCKERNAN RM BARNES NM
Citation
S. Fletcher et al., EVIDENCE THAT PORCINE NATIVE 5-HT3 RECEPTORS DO NOT CONTAIN NICOTINICACETYLCHOLINE-RECEPTOR SUBUNITS, Neuropharmacology, 37(3), 1998, pp. 397-399
Citations number
10
Categorie Soggetti
Pharmacology & Pharmacy",Neurosciences
Journal title
Neuropharmacology → ACNP
ISSN journal
00283908
Volume
37
Issue
3
Year of publication
1998
Pages
397 - 399
Database
ISI
SICI code
0028-3908(1998)37:3<397:ETPN5R>2.0.ZU;2-M
Abstract
The present investigation utilised monoclonal antibodies directed agai nst subunits of the nicotinic acetylcholine receptor in immunoblot and immunoprecipitation studies, which failed to demonstrate that the nat ive 5-hydroxytryptamine(3) (5-HT3) receptor complex purified from porc ine brain contains the alpha(1), alpha(3), alpha(4), alpha(5), alpha(7 ), or beta(2) subunits of the nicotinic acetylcholine receptor. (C) 19 98 Elsevier Science Ltd. All rights reserved.