ON THE METALATION OF 2-ISOPROPYLPYRIDINE

Authors
PASQUINET E ROCCA P MARSAIS F GODARD A QUEGUINER G
Citation
E. Pasquinet et al., ON THE METALATION OF 2-ISOPROPYLPYRIDINE, Tetrahedron, 54(30), 1998, pp. 8771-8782
Citations number
54
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
54
Issue
30
Year of publication
1998
Pages
8771 - 8782
Database
ISI
SICI code
0040-4020(1998)54:30<8771:OTMO2>2.0.ZU;2-W
Abstract
2-Isopropylpyridine has been successfully metallated and functionalize d by using potassium diisopropylamide (KDA). Subsequent functionalizat ion has been achieved with a wide range of electrophiles and good to e xcellent yields have been obtained. The action of other potassium or s odium bases has also been investigated. (C) 1998 Elsevier Science Ltd. All rights reserved.