Our objective was to construct a nomogram of the fetal lingual size in
early pregnancy and to assess the size of the tongue in abnormal fetu
ses. The lingual width was measured by using transvaginal ultrasonogra
phy in 80 normal fetuses at 13 and 18 weeks' gestation. In addition th
e tongue was measured in 22 fetuses at these gestational ages who had
an abnormal karyotype or oro-facial malformations. A linear relationsh
ip was found between the lingual width and gestational age in normal f
etuses. The lingual size was within the normal range in cases of triso
my 13: trisomy 21 and Turner syndrome. A small tongue was observed in
fetuses with micrognathia. Correlation between lingual width and gesta
tional age was observed in early pregnancy. The relationship between t
he size of the tongue and ore-facial malformations needs further evalu
ation. (C) 1998 John Wiley & Sons, Ltd.