A 62-year-old woman presented with raised intracranial pressure and fe
atures of a right cerebellopontine angle tumour with extension into th
e right middle cranial fossa. The patient died before a surgical excis
ion could be performed. The autopsy revealed a primary esthesioneurobl
astoma of the sphenoid sinus eroding the petrous bone and extending in
to the middle cranial fossa with metastatic tumour in the liver, and p
aratracheal and hilar lymph nodes. Although rare, esthesioneuroblastom
a must be considered in the differential diagnosis of petrous-sphenoid
lesions.