Kl. Dueholm, A STRATEGIC ANALYSIS OF PATENTS COVERING RECEPTORS AND THEIR USE AS RESEARCH TOOLS FILED SINCE 1993 BY 3 MAJOR COMPANIES, Expert opinion on therapeutic patents, 8(7), 1998, pp. 871-888
A wide range of different receptors have been patented by Takeda, Merc
k and Human Genome Sciences - each the assignee of ca. 30 patent famil
ies relating To receptors and published in and after 1993. Many of the
patented receptors are G-protein-coupled receptors. The strategies fo
llowed by these three major companies when patenting receptors are dis
cussed. Their strategies differ considerably and range from the extens
ive use of functional reach-through claims by Human Genome Sciences to
Takeda's strategy of frequently filing only in Japan, possibly using
the Japanese patent application as a prophylactic publication. When re
ceptors are patented in only one country by these three and other comp
anies, the USA or Japan is chosen most frequently whereas European cou
ntries are almost never chosen.