We studied the acquisition of bone mineral and related changes in body
mass, pubertal status, and sex hormones in 75 healthy prepubertal and
pubertal girls aged 7.5-16 years. Bone mineral density of the lumbar
spine (L-l, L-2, L-3, L-4) was measured in children by quantitative co
mputerized tomography, Skeletal mineralization accelerated markedly at
puberty. Age, weight, height, and body mass index (BMI) were highly c
orrelated with bone mineral density.