We describe a boy with Hashimoto's thyroiditis and Addison's disease w
ho was initially hypothyroid, developed hyperthyroidism and eventually
became euthyroid, A rise and fall in thyroid binding inhibitory immun
oglobulin and thyroid stimulating antibodies were demonstrated to have
correlated with the appropriate changes in thyroid status, The fact t
hat Hashimoto's thyroiditis can evolve in such a way emphasizes the im
portance of lifetime follow-up in these patients.