H. Moumouni et al., SIDEROSIS IN ALVEOLAR MACROPHAGES - A STU DY IN A SERIES OF 360 BRONCHOALVEOLAR LAVAGES, Pathologie et biologie, 41(7), 1993, pp. 604-609
360 consecutive bronchoalveolar lavage fluids (BAL) were studied using
semi-quantitative method described by GOLDE (GOLDE score). 44 hemosid
erosis were detected (12%). Most of them corresponded to massive alveo
lar hemorrhage (AH). Depending on pathological contexts, we distinguis
hed three main groups of AH frequency : a group high frequency (around
40%), an intermediate group (10%) and a low frequency group with less
than 5%. Matching cytological results with clinical and radiological
datas, revealed that AH was often too late diagnosed because inconstan
cy of typical clinical and radiological signs. Even with a variable pr
ognosis related to different physiopathological mechanisms, AH evoluti
on is unpredictable. The authors suggest thus BAL cytological examinat
ion may systematically include a research of hemosiderosis in AH high
frequency groups.