NEW N-ETHANETHIOL PYRROLES AS RADIOPROTECTORS

Authors
LAWHO,"PERA MH TAILLANDIER G FATOME M LAVAL JD LECLERC G
Citation
Mh. Lawho,"pera et al., NEW N-ETHANETHIOL PYRROLES AS RADIOPROTECTORS, European journal of medicinal chemistry, 28(9), 1993, pp. 703-707
Citations number
20
Categorie Soggetti
Chemistry Medicinal
Journal title
European journal of medicinal chemistry → ACNP
ISSN journal
02235234
Volume
28
Issue
9
Year of publication
1993
Pages
703 - 707
Database
ISI
SICI code
0223-5234(1993)28:9<703:NNPAR>2.0.ZU;2-B
Abstract
Seventeen N-ethanethiol pyrroles have been prepared and tested as radi oprotective agents. This is the first time that pyrrole compounds with radioprotective activity have been reported. The dimethyl pyrrole der ivative 3a and its corresponding disulfur 4a exhibited strong long-las ting effects.