DELAYED POSTANESTHETIC RECOVERY FROM A PO SSIBLE INTERACTION BETWEEN MIDAZOLAM AND FAMOTIDINE

Citation
P. Barrau et al., DELAYED POSTANESTHETIC RECOVERY FROM A PO SSIBLE INTERACTION BETWEEN MIDAZOLAM AND FAMOTIDINE, Annales francaises d'anesthesie et de reanimation, 17(5), 1998, pp. 361-364
Citations number
19
Categorie Soggetti
Anesthesiology
ISSN journal
07507658
Volume
17
Issue
5
Year of publication
1998
Pages
361 - 364
Database
ISI
SICI code
0750-7658(1998)17:5<361:DPRFAP>2.0.ZU;2-G
Abstract
We report the case of a 79-year-old woman, in chronic renal insufficie ncy who recovered from anaesthesia after a delay of 24 hours, after fl umazenil (Anexate(R)) administration. She was given famotidine (Pepdin e(R)) the day before surgery. Midazolam was administered for premedica tion (5 mg per os) and for the induction of anaesthesia (2 mg intraven ous). Among the various causes of delayed recovery in this elderly pat ient, an interaction between midazolam and famotidine is discussed. (C ) 1998 Elsevier, Paris.