''Critical'' according to the Oxford dictionary means: a ''turning poi
nt'' where an acute change for better or worse may be anticipated. Thu
s, the meaning of the word ''critical'' complies with its use in relat
ion to ischaemia. We don't really know, prospectively, what will happe
n to the critically ischaemic limb, whether it will improve or worsen.
The answer to the question ''How critical is critical leg ischaemia (
CLI)?'' must be: ''We don't know!'' The addition of ankle systolic pre
ssure as an objective haemodynamic measurement has not made the defini
tion of the Second European Consensus Group significantly better than
the original Fontaine classification, grade III and IV. For clinical p
ractice the Fontaine classification will be sufficient. For scientific
purposes macro- and microcirculatory assessments and information abou
t the patient's risk profile should be added.