Polymerization of the melanoidin in a heated onion juice and a model s
ystem of glucose and glycine was investigated by dialysis and gel filt
ration chromatography on a Sephadex G-25 column. The melanoidin in a h
eated-onion juice was eluted in the fractions of smaller molecular wei
ght than those of sugar and amino acid, with a similar chromatography
to caramel rather than these of model melanoidin and soy sauce. Adding
onion juice to the model system of glucose and glycine, the ratio of
dialyzable melanoidin in the whole melanoidin increased. The inhibitor
y effect of onion juice on the polymerization of melanoidin was specul
ated.