THEORY AND METHODOLOGY OF ANTIBIOTIC EXTRACTION FROM BIOMATRICES

Citation
Rw. Fedeniuk et Pj. Shand, THEORY AND METHODOLOGY OF ANTIBIOTIC EXTRACTION FROM BIOMATRICES, Journal of chromatography, 812(1-2), 1998, pp. 3-15
Citations number
66
Categorie Soggetti
Chemistry Analytical","Biochemical Research Methods
Journal title
Volume
812
Issue
1-2
Year of publication
1998
Pages
3 - 15
Database
ISI
SICI code
Abstract
A short review on the basic theory and practices of the extraction and clean-up of agricultural antibiotics from biomatrices is presented. F or the analysis of residues of ionophores, beta-lactams, macrolides, c hloramphenicol, aminoglycosides, tetracyclines and peptide antibiotics , the use of solid-phase extraction has become nearly ubiquitous as pa rt of the basic extraction methodology. The majority of the methodolog ies for these compounds report recoveries greater than 70%, with relat ive standard deviations usually less than 15%. Each of the antibiotic classes, as well as antibiotics within each class, have unique chemist ries that must be taken into account when developing a viable extracti on method. (C) 1998 Elsevier Science B.V. All rights reserved.