USE OF LIQUID-CHROMATOGRAPHY MASS-SPECTROMETRY IN THE ANALYSIS OF RESIDUES OF ANTIBIOTICS IN MEAT AND MILK

The advent of affordable LC-MS systems has led to a massive increase i n the number of publications describing quantitative methods for the a nalysis and confirmation of veterinary drug residues. The lack of vola tility and thermal instability of many antibiotics makes LC-MS the met hod of choice for their analysis. In this review, analytical methods f or the determination of residues of each of the major classes of antib iotics are presented. (C) 1998 Elsevier Science B.V. All rights reserv ed.