The rheumatoid polyarthritis (cP) is a chronic inflammatory disease wi
th unknown etiology. A comparison between human and canine cP is possi
ble, especially because of the similar immunologic response (Rheumatoi
d factor, cytokine activity and T-cell dependance) and the poor respon
se to any therapy. The clinical diagnostic procedure involves serologi
cal diagnostics (Rheumatoid factor and antinuclear antibodies) and a d
etailed orthopedic examination together with synovial fluid cytology.
Radiological examinations can not be used for causal diagnostics but a
re very useful to follow up examinations. A tentative diagnosis of cP
can be achieved together wit a newly developed rheumatoid factor test.