Objective. To develop a methodology for generic, comprehensive biomech
anical profiling of hand-intensive tasks. Design. Based on a multifact
orial model of work-related musculoskeletal disorder development, a me
thod was developed for continuous, simultaneous measurement of relevan
t variables (wrist and finger joint position, force, muscle activity,
and carpal tunnel pressure). Joint dynamics and tendon travel were der
ived. Background. Few generic dose-response relationships have been id
entified for work-related musculoskeletal disorders. This may improve
if methodologies are developed that quantify multiple factors along se
veral dimensions (means, cumulative exposure, etc.). This requires con
tinuous, simultaneous measurements, and facilitates examination of int
eractions. Methods. Five touch-typists were instrumented to quantify t
heir biomechanical profiles using the methodology, and to evaluate the
sensitivity of the method to various work organization/design conditi
ons. Results. The method captured individual and group responses to de
sign conditions and revealed interactions and trade-offs between respo
nse variables. Carpal tunnel pressure was found to be sensitive to rad
ial-ulnar wrist posture. Conclusions. Multi-variable biomechanical pro
filing can provide insight into effects of work design on workers; how
ever, to achieve statistical significance large numbers of subjects ar
e needed.