H. Neittaanmaki et al., SKIN ATROPHY OF THE EYELID INDUCED BY TOPICAL OPHTHALMIC CORTICOSTEROIDS, Acta ophthalmologica Scandinavica, 76(3), 1998, pp. 372-373
A case of eyelid skin atrophy caused by long-term application of topic
al ophthalmic corticosteroids for chronic uveitis is reported. Skin pu
nch biopsy of the uveitic eye showed moderate atrophy of both epidermi
s and dermis (compared to normal skin on the other eye) resulting from
a reduction in the three main fibrous components of the skin, namely
type I and type III collagens, and elastic fibers. To our knowledge, t
his is the first report of skin atrophy in this association.