L. Brochard, USE OF NONINVASIVE POSITIVE PRESSURE VENT ILATION FOR CARDIOGENIC PULMONARY-EDEMA IN EMERGENCY CARE UNITS, La Presse medicale, 27(22), 1998, pp. 1105-1107
The work reported by I'Her et ai. in this issue of io Presse Medicale
demonstrates the feasibility of applying simple intensive care techniq
ues in situations frequently encountered in emergency care units. Thes
e authors used a face mask for continuous positive pressure ventilatio
n in patients over 70 years oi age admitted for respiratory distress r
elated to cardiogenic pulmonary edema. in these elderly patients, the
authors noted an improvement in blood gases, respiratory rate and hear
t rate and did nor observe any secondary effect Acute respiratory fail
ure was cured in 90% of the cases without referral to the intensive ca
re unit The mechanism of action of continuous positive airway pressure
, or spontaneous ventilation with positive expiratory pressure, is dif
ferent from simple oxygen therapy. Two mechanisms are intimately relat
ed. The main effect is ventilatory assistance resulting from a ''re-ae
ration'' of the pulmonary parenchyma which increases compliance and re
duces work required to overcome elastic retraction forces. likewise th
e increased pulmonary volume reduces pulmonary resistance. Positive ai
rway pressure also has an effect on left ventricular function; indeed,
after load is reduced by the reduction in the large negative intratho
racic pressure swing. lower energy expenditure required for respiratio
n also greatly reduces total oxygen consumption and improved blood gas
es favor oxygen supply to the myocardium. The contraindications of con
tinuous positive airway pressure are related to abnormal central of th
e upper airways and major hemodynamic disorders. Prudence is also requ
ired in case of shock due to the risk of major respiratry muscle fatig
ue. The question could also be raised as to the risk in elderly patien
ts where cardiogenic pulmonary edema is often associated with a certai
n degree of chronic bronchitis. It is now known that these patients ha
ve an intrinsic positive expiratory pressure which considerably increa
ses respiratory work Symptomatic treatment in this type of disorder is
mechanical and continuous positive airway pressure diminishes this wo
rk. Cardiogenic pulmonary edema in the elderly is thus an excellent in
dication for spontaneous Ventilation with positive expiratory pressure
. improvement in these simple techniques, their widespread use and a b
etter understanding of their limitations remain important challenges f
or the future. (C) 1998, Masson, Paris.