PLEURAL GRANULOCYTIC SARCOMA - A CASE-REP ORT AND LITERATURE-REVIEW

Citation
G. Vottero et al., PLEURAL GRANULOCYTIC SARCOMA - A CASE-REP ORT AND LITERATURE-REVIEW, Revue des maladies respiratoires, 15(3), 1998, pp. 300-302
Citations number
16
Categorie Soggetti
Respiratory System
ISSN journal
07618425
Volume
15
Issue
3
Year of publication
1998
Pages
300 - 302
Database
ISI
SICI code
0761-8425(1998)15:3<300:PGS-AC>2.0.ZU;2-#
Abstract
The granulocytic sarcoma is a rare and extramedullary tumor, which is composed of granulocytic precursor cells. The diagnosis remains diffic ult. Infectious disease are often associated with leukemic processes. Combination of clinical, radiological and pathological findings,ps nr- e useful for, diagnosis, On gross examination the tumor appears green. The detection of myeloperoxidases and the presence of immature eosino phils can help histological analysis. Granulocytic sarcoma occurs befo re or during an acute leukemia. It is treated like an acute leukemia. Prosnostic is greatly improved by early diagnosis and treatment. The l ack of cytogenetic abnormalities is associated with a prolonged surviv al. We describe a new case of rapidely growing pleural granulocytic sa rcoma. The uncommon modifications of chromosome 5 long arm in this cas e could explain the immature eosinophil reaction in that tumor.