Sl. Guo et al., SYNTHESIS, CHARACTERIZATION, AND RADICAL SCAVENGING EFFECTS OF POLYNUCLEAR THIOLATE COMPLEXES, Journal of inorganic biochemistry, 70(1), 1998, pp. 7-10
Three thiolate complexes (Me4N)(2)[M-4(o-SC6H4CH3)(10)], [M = Zn (1);
Cd (2)] and [c-mu(4)-S)(SCH2Ph)(12)S4Zn8] (3) were synthesized and cha
racterized by elemental analyses, IR, and H-1 NMR Spectroscopic techni
ques. The suppression abilities of complexes for the hydroxyl radical
(OH .) and TEMP (HO-N-O .) were determined by EPR. The former were als
o measured by its reaction with 3-methylthiobutyraldehyde (MBA) to giv
e propylene and methane analyzed by GC. The results show that the comp
lexes possess selectively scavenging effects: on the hydroxyl radicals
, abilities decreased across the series 3 > NMT > 2 approximate to 1 (
NMT = native metallothionein), whereas, on TEMP radicals, the order wa
s 1 > 3 > NMT > 2. (C) 1998 Elsevier Science Inc. All rights reserved.