S. Ganesan et al., INVASIVE LARYNGEAL CANDIDIASIS - A CAUSE OF STRIDOR IN THE PREVIOUSLYIRRADIATED PATIENT, Journal of Laryngology and Otology, 112(6), 1998, pp. 575-578
Upper airway obstruction is always a serious condition. In patients wh
o have previously been irradiated for a laryngeal malignancy, it norma
lly implies either residual or recurrent disease. We report a case of
strider due to invasive laryngeal candidiasis in a patient who had und
ergone radiotherapy for a T-1a N-0 squamous cell carcinoma of the glot
tis eight months earlier. Extensive investigation failed to identify r
ecurrence of disease and the patient responded to prolonged topical an
tifungal therapy. Infection with Candida species is most frequently fo
und in debilitated or immunocompromised patients. Although cases of up
per airway obstruction in children secondary to idiopathic laryngeal c
andidiasis have been reported, to our knowledge no such presentation h
as been described in adults. This report highlights the difficulty of
diagnosis and treatment. Familiarity with candidal infection is import
ant for early diagnosis and appropriate treatment.