R. Machemer et Uh. Steinhorst, RETINAL SEPARATION, RETINOTOMY, AND MACULAR RELOCATION .1. EXPERIMENTAL STUDIES IN THE RABBIT EYE, Graefe's archive for clinical and experimental ophthalmology, 231(11), 1993, pp. 629-634
An animal model in the rabbit eye was utilized to study mobilization a
nd relocation of the fovea as a potentially;beneficial surgical approa
ch to age-related macular disease. After lentectomy and vitrectomy, th
e retina was completely separated from the pigment epithelium by means
of infusion into the subretinal space. A 360 degrees peripheral retin
otomy was performed. The retina was rotated up to 60 degrees around th
e optic nerve as axis and reattached. Scanning and transmission electr
on microscopy revealed the relative intactness of outer segments and p
igment epithelium after this procedure, both acutely and 3 days follow
ing reattachment.