ASSESSING THE SUITABILITY OF GASTRIC-CARCINOMA FOR LIMITED RESECTION - HISTOLOGIC DIFFERENTIATION OF ENDOSCOPIC BIOPSY

Histologically differentiated adenocarcinoma satisfies one of the crit eria for limited surgery for mucosal carcinoma of the stomach; however , the histology of the endoscopic biopsy specimen is often different f rom that of the resected specimen. The medical records of 1018 early g astric carcinomas were retrospectively analyzed to investigate the rel ation between the histologies of biopsy and resected specimens. Regres sion analysis showed that the histologies of biopsy specimens were sig nificantly related to those of resected specimens (r = 0.916, n = 5,p = 0.0288) for the mucosal carcinomas, but their relation was not signi ficant for the submucosal carcinomas (r = 0.677, n = 5,p = 0.2091). By analyzing the 344 differentiated mucosal carcinomas, moderately diffe rentiated tubular adenocarcinomas were seen to be frequently Less diff erentiated at resection. The histology of the biopsy specimens from mu cosal carcinoma of the stomach grossly satisfies one of the criteria f or limited surgery, but moderately differentiated adenocarcinoma may n ot be suitable for this treatment.